Fundamentals of Biochemistry, a new free LibreText book for undergraduate courses


This article was originally published here

FASEB J. 2022 May;36 Suppl 1. doi: 10.1096/fasebj.2022.36.S1.R4590.


We are developing a new fee-based online biochemistry text, Fundamentals of Biochemistry, as part of the LibreTexts project ( under a grant funded by the Ministry of Education to produce textbooks for all chemistry required for a four-year ACS certified degree. This text covers a full year sequence of biochemistry and will be available in Fall 2022. The book could serve traditional, ASBMB-certified, and ACS-certified majors, as well as students taking a one-semester course. Adopting instructors could create custom text from the content. Characteristic of all LibreText books, Fundamentals of Biochemistry will be open to everyone via the Internet and completely free, as everyone should have access to the knowledge. It is comprehensive and up-to-date, as new materials are easily added. It has been and will be built with a community of active collaborators. LibreText book collections have served 223 million students and saved them $31 million, an undue burden on our students and society. Some of the features of Fundamentals of Biochemistry include interactive 2D math graphs with sliders that allow constants to be changed with immediate graph updates; Interactive molecular models using iCn3D ( which allows students to view and interact with rendered structures; Built-in VCell models ( that allow users to display time graphs for simple to complex reactions; Animations to accompany VCell progress curve graphs; Chapter sections on metabolic control assays which will include Vcell models; Added new materials such as RNA glycans, SARS-CoV-2 structures, etc. The text will be available for adoption by Fall 2022. We continue to need assistance in drafting key features and in an ongoing process of updating, particularly in these areas: end-of-chapter issues and of chapters (hopefully based on research literature) mechanisms of your favorite enzymes or topics you don’t find well presented in other texts inclusive and diverse content climate change, health disparities, addiction, etc.

PMID:35555895 | DOI:10.1096/fasebj.2022.36.S1.R4590


Comments are closed.